Melittin, a honeybee venom-derived antimicrobial peptide, may target methicillin-resistant Staphylococcus aureus

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Melittin, a honeybee venom-derived antimicrobial peptide, may target methicillin-resistant Staphylococcus aureus

Methicillin‑resistant Staphylococcus aureus (MRSA) is difficult to treat using available antibiotic agents. Honeybee venom has been widely used as an oriental treatment for several inflammatory diseases and bacterial infections. The venom contains predominantly biologically active compounds, however, the therapeutic effects of such materials when used to treat MRSA infections have not been inve...

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Antibacterial Activity and Antibiotic-Enhancing Effects of Honeybee Venom against Methicillin-Resistant Staphylococcus aureus.

Methicillin-resistant Staphylococcus aureus (MRSA), along with other antibiotic resistant bacteria, has become a significant social and clinical problem. There is thus an urgent need to develop naturally bioactive compounds as alternatives to the few antibiotics that remain effective. Here we assessed the in vitro activities of bee venom (BV), alone or in combination with ampicillin, penicillin...

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Methicillin Resistant Staphylococcus aureus

Etiology Staphylococcus aureus is a Gram positive, coagulase positive coccus in the family Staphylococcaceae. Methicillin-resistant S. aureus (MRSA) strains are resistant to methicillin and essentially all other beta-lactam antibiotics. MRSA isolates are genetically heterogeneous. 1 Some strains, which are called epidemic strains; are more prevalent and can spread within or between hospitals an...

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Methicillin Resistant Staphylococcus aureus

Staphylococcus aureus is an opportunistic pathogen often carried asymptomatically on the human body. Methicillin-resistant S. aureus (MRSA) strains have acquired a gene that makes them resistant to all beta-lactam antibiotics. Hospital-associated strains of this organism are serious nosocomial pathogens that have become resistant to most common antibiotics, and treatment can be challenging. Com...

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Methicillin-resistant Staphylococcus aureus

received much attention over the past 30 years because of its increasing incidence and the morbidity and excess hospital stay length associated with MRSA infection. Th e current controversy about the eff ectiveness of control measures, notably screening, derives from the confl icting results of available studies, lack of well-designed controlled studies, and concomitant use of several intervent...

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ژورنال

عنوان ژورنال: Molecular Medicine Reports

سال: 2015

ISSN: 1791-2997,1791-3004

DOI: 10.3892/mmr.2015.4275